There are really no good reasons to feed live mice to a snake or other animal. Some pet owners believe live mice are more natural for the snake but the majority of snakes will eat frozen & thawed mice. Live food can also severely injure or even kill your pet. These mice are fighting for their lives, there is nothing stopping them from biting or scratching it's predator which can be painful or deadly for the predator. Live food can also transmit mites or diseases to your pet.
Snakes are able to read an animals heat signature, this is how they know when food is near by and why it's important to warm up frozen food before feeding. Cold or frozen mice can cause constipation or regurgitation in a snake. The risk of disease transferred from frozen food is very minimal, much less than that of live food. You can often buy bulk orders of frozen for much less than you would pay for live. You could buy a pack of 50 Frozen mice for 69.99 from Petsmart, for 69.99 you could buy an average of 13 Live Mice.
Live mice and rats used as food live the last minutes of their lives in pain and fear.
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